Bill Sellers is a core institute member of the Broad Institute of MIT and Harvard and serves as director of the institute's Cancer Program. He is also a Professor of Medicine at the Dana-Farber Cancer Institute and Harvard Medical School. Bill spent his academic career at the intersection of cancer biology and genomics, investigating mechanisms of tumor development. He collaborated with Matthew Meyerson to initiate the Broad’s first major cancer genomic efforts, leading to the discovery of EGFR mutations in lung cancer and the oncogenic role of MITF in melanoma.
Previously, Sellers served as VP/Global Head of Oncology at Novartis Institutes of BioMedical Research, where he oversaw small molecule, antibody-based and cell therapy drug discovery efforts in oncology. In addition, he initiated and led the Cancer Cell Line Encyclopedia project in collaboration with the Broad Institute.
He earned his B.S. in biology from Georgetown University and his M.D. from University of Massachusetts Medical School. He completed his internship and residency in internal medicine at University of California San Francisco before completing a clinical oncology fellowship at Dana-Farber. He completed postdoctoral training in the labs of Dr. David Livingston and William G. Kaelin.
Jayu joined Sellers lab in April 2022 as a Research Scientist in the paralog team. Jayu is specifically interested in identifying tumorigenesis and drug resistance mechanisms in genetically-defined models. She is a huge dog lover and has three adopted dogs back home in Taiwan! She loves music (all kinds of music, including pop music and musicals) and used to dance in her free time.
Eiman is a postdoctoral fellow. She is interested in interrogating cancer paralog dependencies, and developing approaches in mouse models to identify potential therapeutic targets. Outside the lab, she is a loving mother and enjoys traveling, scuba diving, cooking and listening to music.
Liang is a graduate student. He is pursuing a Ph.D. through the Biological and Biomedical Sciences program at Harvard. Liang is interested in using novel functional genomic technologies and patient multi-omics data to discover new therapeutic-exploitable cancer vulnerabilities. Outside of the lab, he enjoys basketball, scientific blog writing, and playing poker.
- B.A. Biology — Macalester College
Saireudee (Gal) Chaturantabut
Saireudee (Gal) is a postdoctoral fellow. She grew up in Bangkok, Thailand. Gal is interested in investigating cancer dependency pathways to enable the discovery of new therapeutics for cholangiocarcinoma. Outside of the lab, Gal enjoys reading, traveling, and outdoor activities.
- Ph.D. Molecular and Cellular Biology — Harvard University
Eunice is a postdoctoral associate. Eunice is interested in understanding the molecular underpinnings and oncogenic signaling network rewiring involved in drug response and resistance in cancer. Outside of the lab, Eunice enjoys binging TV shows and eating sweets.
- Ph.D. Pharmacology — Yale University
Hubert Huang is a postdoctoral associate. He grew up in Taiwan. In the Sellers Lab, he is pursuing the identification of cancer vulnerabilities, as well as developing methods to better understand ubiquitin biology. Outside the lab, he enjoys playing board games with friends (particularly Eurogames), playing video games, and watching movies and TV series.
- Ph.D. Chemical Biology — Harvard University
Tian-Yu Song is a postdoctoral associate in Sellers lab. He is always intrigued by how cancer escapes clearance by therapeutic agents or host immunity. To answer this question, he has performed and is still designing multiple CRISPR library screenings in engrafted tumors, organoids, cancer-immune cell co-cultures and drug-induced cytotoxicity systems. Outside the lab, he enjoys reading, playing genshin impact and board games with friends, and watching basketball and soccer. Now he is trying to learn about football and fitness.
Ph.D. Cell Biology — Zhejiang University
Moore van Tienen
Moore is a postdoctoral fellow. He is from Amsterdam, the Netherlands. Currently, he is interested in developing functional genomic approaches to discover novel therapeutic opportunities in cancer. In his free time, Moore enjoys cooking, traveling, hiking, and cuddling his mom’s dachshund Vanja.
- Ph.D. Molecular Biology — University of Cambridge (MRC Laboratory of Molecular Biology)
Shadwa is a Research Associate I in the Sellers Lab. In her free time, she enjoys reading, playing board games, cooking, traveling, and exploring the city
- B.S. Biology – University of North Carolina at Chapel Hill
Dennie is a research scientist and lab manager for the Sellers lab where they are both seeking to enable great science through organizational and overall support as well as leverage a long history of translational cancer research to contribute in meaningful and hands-on ways to the discovery of novel and impactful therapeutics against cancer. Outside the lab, they like mornings (especially with good coffee and big breakfasts), gardening and camping.
- M.S. Biology – University of Pennsylvania
Sydney is a Research Associate I in the Sellers Lab. In her free time, she enjoys painting, drawing, knitting, cooking, and listening to live music.
- B.S. Biochemistry — Simmons University
Julian Pozniak is the Administrative Lead for the Sellers Lab. Beyond his work in the lab, Julian teaches private piano and voice lessons to Boston-area students. For fun, he can often be found cooking from his collection of cookbooks, gaming online, or watching classic movies.
- B.A. in Music and Political Science – Carleton College
- M.M. in Music Composition – New England Conservatory of Music
Ryan is a Research Associate I in the Sellers lab. In his free time, he likes to fold origami, explore the outdoors and hike, and play video games.
B.S. Chemical Biology – Brandeis University